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1.
1. short for "organic chemistry."

2. an extremely difficult course that one takes, usually during the second year of college for prospective Pre-Med students. It is associated as a "weeder" class for hopeful students, as many people drop the class before they complete it.
"Holy fuck man, I don't get any of this orgo stuff at all."

"Yeah, ikr?"

"I want to drop this class, but I don't wanna look like a fucking retard. What should I do?"

"Idk man. Idk."
Beküldő: Omniscient Dumb Fuck 2011. november 16.
 
2.
A 15" penis shoved up the ass of Pre-Med (or Chemistry) students repeatedly over the course of two semesters, the first semester being a reasonably gentle fucking and the second semester coming with the potential for serious gastrointestinal problems. If this does not occur, one's anal passageways are not appropriately loose to accomodate the ass reaming given by the MCAT.

Short for Organic Chemistry, the study of the naming, structure, and synthesizing of carbon-based molecules. It is said that when Pre-Med students die and go to hell, they're perpetually in Orgo Lab.
Bobby wanted to go to Med School, but then he sat Orgo and now he can't sit down because his ass still hurts.

Tommy went to a school where Orgo is easy and got an A, but scored a 21 on the MCAT, so he won't be going to Med School.

"I can't do that much for Rush, bro. Taking Orgo means that I can't drink five nights a week."
Beküldő: doesthislabcoatmakemelookfrat? 2013. június 24.
 
3.
Sometimes referred to as ochem by holier than thou west coast students when referring to organic chemistry.
I can't go surfing dude! I have to study for my orgo exam tomorrow.
Beküldő: The Boomhower 2011. április 11.
 
4.
A girl who is not inclined to partake in sexual activities and must therefore vacate the premises.
Ex. 1:

Bro 1: to Orgo Girl: You baby you DTF?
Orgo Girl: No way you perv.
Bro 1: Well then you must leave... OrGo.

Ex. 2:
Bro 1: Yo is she DTF?
Bro 2: Nah she's Orgo dude.
Beküldő: Carltonbanks 2010. október 15.
 
5.
orgo

A term for "organic chemistry" that stuck up rich ass east coast students use because apparently the east coast is too good for conventional usage of abbreviations. Many east coast students like to call it a "weeder" class for premed students, but on the west coast, pre-med students know better than to be discouraged by a single class, so such a trend does not exist.

East coast student: "Hey what do you think of orgo?"
West coast student: "Sorry, we only speak English over here. I don't know about any orgo, but ochem is a pretty good class to take."
East coast student: "Hey what do you think of orgo?"
West coast student: "Sorry, we only speak English over here. I don't know about any orgo, but ochem is a pretty good class to take."
Beküldő: relaxin' 2010. október 12.
 
6.
Abbreviation for "Organic" in the context of organic chemistry - regarded as among the simplest of many upper-level ivy-leauge chemistry sequences. Also commonly employed as a weed-out class for premedical students. However, the material is simple, and the tests are easy. Especially lab commandant's Parr-Hydrogenation tests.
Dude, that orgo final was mad easy.
Beküldő: NUndergrad 2006. január 16.